Engineering multicellular systems by cell–cell communication

Communication theory and multicellular biologyw

ion of communication theory as an organising principle for multicellular biology could be realised. We highlight the inherent ability of communication theory to be blind to molecular and/or genetic mechanisms. We describe selected applications that analyse the physics of communication and use energy efficiency as a central tenet. Whilst communication theory has and could contribute to understan...

Priority Traffic Modeling in Multicellular Communication Networks

In this paper we analyze a cellular communication environment which offers specific users priority access to network resources. We foresee a finite number of widespread disparate mobiles moving in a geographical region covered by a finite set of cells. Each user belongs to a class characterized by a specific service, load and mobility profile. In this paper we will consider two classes, namely ...

Satellite Communication Systems Engineering : LEO , MEO , GEO

This three-day course is designed for satellite communications engineers, spacecraft engineers, and managers who want to obtain an understanding of the “big picture” of satellite communications. Each topic is illustrated by detailed worked numerical examples, using published data for actual satellite communications systems. The course is technically oriented and includes mathematical derivation...

Evaluation SS06 Seminar: Engineering Complex Communication Systems

Communication shapes sensory response in multicellular networks.

Collective sensing by interacting cells is observed in a variety of biological systems, and yet, a quantitative understanding of how sensory information is collectively encoded is lacking. Here, we investigate the ATP-induced calcium dynamics of monolayers of fibroblast cells that communicate via gap junctions. Combining experiments and stochastic modeling, we find that increasing the ATP stimu...